产品货号：
Z20797
中文名称：
MPG抗体
英文名称：
Anti-MPG Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MPG Antibody |
| 指标别名 | 3 alkyladenine DNA glycosylase;AAG;ADPG;anpg;APNG;CRA36.1;MDG;Mid1;MPG;N methylpurine DNA glycosylase;PIG11;PIG16 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | MPG |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human MPG(228-243aa NKSFDQRDLAQDEAVW),different from the related mouse sequence by two amino acids,and from related rat sequence by one amino acid. |
| 实际分子量 | 33KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MPG(N-methylpurine-DNA glycosylase) also known as MDG,3-METHYLADENINE DNA GLYCOSYLASE,3MeAde DNA GLYCOSYLASE,AAG or APNG.The MPG gene is mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines.The MPG gene was expressed in all cell lines and tissues examined,but was found at particularly high levels in a colon adenocarcinoma cell line(HT29).The completely characterized human MPG gene was found to span 7 to 8kb of genomic DNA and to be localized 75kb upstream of the embryonic zeta-globin gene.To assess the contribution of Apng to the repair of several mutagenic lesions in vivo,Hang et al.(1997) biochemically analyzed cell-free extracts of tissues from mice with a targeted deletion of the Apng gene.Following treatment with DNA-methylating agents,increased persistence of 7-methylguanine(meG) was found in liver sections of APNG knockout mice in comparison with wildtype mice,demonstrating an in vivo phenotype for the APNG-null animals. |
| Uniprot ID | P29372 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | N-methylpurine-DNA glycosylase |
| 蛋白名全称 | DNA-3-methyladenine glycosylase |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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